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Modulation of the p38 MAPK pathway by anisomycin promotes ferroptosis of hepatocellular carcinoma through phosphorylation of H3S10

Metabolites 12:50

The pro-drug form of L-DON, sirpiglenastat (DRP-104), attempts to avoid the toxicity that is often associated with L-DON, and when used in combination with gemcitabine, it has been observed to dramatically increase the survival rate of PDAC [89]