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Description

Surprisingly, blockade of CTLA-4 results in a significant increase in IDO expression and activity (234)

Acta Biomed

& Piekoszewski, W

Hadden DR

TSHR CAAR T cells, co-cultured in vitro with anti-TSHR B cells that were transduced by lentivirus, exhibited significant increases in IFN, IL-2, and TNF levels within 24 hours, effectively eliminating autoreactive anti-TSHR B cells without affecting other B cell populations