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432 ChenXet al

Targeting VEGF/VEGFR to decrease the number and function of immunosuppressive cells: Overexpression of VEGF in the TME is associated with intratumoral Tregs, which is associated with a poor prognosis [59]

These fibers, composed of FDA approved polymers such as PLGA and PEO, offer sustained release of probiotics, lactic acid, and hydrogen peroxide

Furthermore, the oligomerization domain mutant Mid51 (R169W) has recently been identified as a potential candidate genetic variant for PD as it can inhibit inter-lysosomal untethering events mediated by MLCSs, resulting in the dysregulation of lysosomal network dynamics (Wong et al., 2022)

doi: 10.1080/01902148.2020.1726529