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Purine catabolism via yagS was most prevalent in the subsurface of site 9.2 (141 tpm), and this activity was attributed to Chloroflexota bacteria and Bathyarchaeaota archaea

Furthermore, cross-sectional analyses based on the National Health and Nutrition Examination Survey (NHANES) confirmed an inverse association between dietary fiber intake and DKD prevalence (9)

One study revealed that leopurine inhibits SLC40A1, reducing its transport efficiency (214)

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