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Baseline vitamin B12 levels before starting metformin Annual monitoring for patients on long-term metformin therapy Consideration of vitamin B12 supplementation if deficiency is detected Antibiotics and Chemotherapy Agents That Affect B12 Metabolism Certain antibiotics and chemotherapy agents can harm vitamin B12 metabolism

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The Bottom Line: Can You Take Semaglutide and Tirzepatide Together Semaglutide and tirzepatide are both powerful medications used in medical weight management, but they are not typically taken together