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The E3 ligase tripartite motif 7 drives the progression of non-alcoholic fatty liver disease by targeting DUSP10 degradation in male mice

Although over 30 years of preclinical studies have shown strong tissue-protective and regenerative properties in in vitro (cell) and in vivo (animal) models, it has only been classified as an Investigational Drug (ID) which can not be used in clinical studies on humans

2) This review completed by Wright et al investigates the development of small molecule AngIV analogs as potential treatments for AD and PD, two debilitating neurodegenerative conditions currently lacking effective disease-modifying therapies

Interpreting available data requires cautioneffects in test tubes do not always translate to clinical outcomes in humans

Guillaumond et al., 2005)