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Concentrations were calculated using a subsequent four-parameter logistic regression based on the standard analyte concentrations using GraphPad PRISM software (Dotmatics, Boston, MA, USA)

[240] reported that the antioxidant azelaic acid can reduce ROS levels, elevate the total antioxidant capacity of AML cells, and exhibit antileukemic effects

Further evidence by Wang et al

The interaction between p53 and MDM2 can be disrupted by NPM1 when NPM1 translocates from the nucleolus to nucleoplasm where NPM1 bound to MDM2 to induce p53 accumulation [19]

doi: 10.1111/jcmm.13735 168 Carmona-RiveraCCarlucciPMMooreELingampalliNUchtenhagenHJamesEet al