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10.3390/molecules28114491 12 BenjamimC

Crystallogr 66 , 213221 (2010)

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Correspondingly, supplement with FAD also rescued GSH levels and GSH/GSSG ratio, as well as suppressed the elevated ROS and lipid peroxidation observed after FADS knockdown (Fig

The main mechanisms of this process are as follows: Through the FLT3-STAT5 signaling axis, the FLT3-ITD mutation directly increases phosphofructokinase platelet-type (PFKP), which in turn promotes glucose uptake, lactate generation, and glycolysis, all of which encourage the rapid proliferation of LSCs