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If available, offer access to pre-exposure prophylaxis (commonly called PrEP): antiviral medications shown to reduce HIV spread from engaging in risky sexual behaviors or high-risk injection drug use (Owens DK et al, JAMA 2019;321(22):22032213)

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Moreover, the capability of neurons to scavenge ROS through an autonomous approach is limited (Table 1)

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This supports the potential of compounded cyanocobalamin/SNAC as a practical alternative for patients who are injection/needle-averse , non-compliant with injections, or seeking a more convenient therapy even if their providers have traditionally used methylcobalamin in injectable form