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Iron chelation mitigates mitochondrial dysfunction and oxidative stress by enhancing nrf2-mediated antioxidant responses in the renal cortex of a murine model of type 2 diabetes

Consequently, this mechanism suppresses the elevation of Fe 2+ , thereby inhibiting ferroptosis in GSCs

[DOI] [PubMed] [Google Scholar] 210.Retout M, Valkenier H, Triffaux E, Doneux T, Bartik K and Bruylants G, ACS Sens, 2016, 1, 929933

rxlist.com Austedo Keywords Valbenazine Trade Name: Ingrezza Drug Class: Rx of Tardive dyskinesia (monoamine depletor) Mechanism of Action: a selective competitive inhibitor of VMAT2, similar to tetrabenazine the monoamine vesicular monoamine uptake transporter (VMAT2) transports (loads) cytoplasmic monoamine neurotransmitters (dopamine, norepinephrine, histamine, serotonin) into presynaptic storage vesicles found in sympathetic nerve terminals