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DNA methylation involves the transfer of a methyl group (CH 3 ) from the universal donor S-adenosylmethionine ( SAM ) to the fifth carbon of a cytosine ( C ), by a DNA methyltransferase ( DNMT ), to produce 5-methylcytosine ( 5-mC )

Conclusion Zinc and selenium are fundamental components of thyroid hormone synthesis, activation, receptor signaling, antioxidant protection, and immune modulation