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Mori, C

Biomaterials 320:122345

MMA is a rare, inherited metabolic disorder characterized by a deficiency in methylmalonyl-CoA mutase (MUT), a mitochondrial enzyme that mediates the final stage of oxidation for valine, isoleucine, and odd-chain fatty acids

These compounds counteract fundamental pathological processes such as oxidative stress, inflammation, endothelial dysfunction, abnormal lipid metabolism, and cardiac remodeling

Indeed, the anticancer ability of dietary fiber is mediated via a few mechanisms including (1) affecting steroid hormone level by reducing circulating androgens and estrogens