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You might feel nervous to bring these symptoms up with your healthcare professional, but take heart: These signs of perimenopause are nothing to be embarrassed about and are incredibly common

Therefore, all the scientific information on its effects is only available from animal and in vitro studies

However, it may not be suitable for everyone, and a medical exam is necessary before starting treatment

When to Take Vitamin B12 Because vitamin B12 is water-soluble, meaning it dissolves in water, its often best taken on an empty stomach with water, said Megan Meyer, PhD, a science communication consultant based in Durham, North Carolina