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Another UPR branch is activated by IRE1, which following their dimerization and autophosphorylation 70 , generates a functional spliced XBP1 ( XBP1s ) 71 that as a transcription factor regulates the expression of numerous genes maintaining ER and metabolic homeostasis 7278 (Figure 2)

Pharmacogenetics of the mycophenolic acid targets inosine monophosphate dehydrogenases IMPDH1 and IMPDH2: gene sequence variation and functional genomics

The molecular mechanism may be related to the upregulation of CXCR2 to promote the phosphorylation of FAK (Wang et al., 2022)

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Human milk lipids