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Melatonin as an anti-oxidant in Liver disease Due to high amounts of intracellular concentrations of glutathione(GSH), superoxide dismutase (SOD), catalase, and lipid soluble antioxidants [40], hepatocytes are stable to injuries caused by Reactive Oxygen species (ROS) and Reactive nitrogen species (RNS)

These changes are structurally conducive to modifying the glianeuron contact areas (133)

Cell Microbiol (2003) 5(9):64960

Although the liver is exceptionally regenerative because it evolved to manage toxins and viruses, modern diets and alcohol have overwhelmed its ability to heal, causing an epidemic of liver damage