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A genomics approach to the comprehensive analysis of the glutathione S-transferase gene family in soybean and maize

Riboflavin also plays a role in thyroxine metabolism, and its deficiency may contribute to mental illness, because riboflavin activates vitamin B6, leading to lower thyroxine levels, reduced hypothalamic serotonin synthesis, and decreased levels of S-adenosylmethionine (SAMe), because of disrupting the folate-methylation pathways involved in SAMe synthesis, all of which are associated with antidepressant effects, consequently, low levels of these compounds may cause depression ( Figure 4 ) (48, 49)

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[DOI] [PubMed] [Google Scholar] 22.Kim J., Chan J.J

At the same time, they may need more of it because the body is dealing with more oxidative stress, more inflammation, and more disease pressure