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The toxicokinetics of APAP can be altered by genetics, dose, diet, age, alcohol and other factors, and these factors make translating biomarkers discovered in omics nonclinical studies to the clinic challenging

It works by preventing the infiltration of tyrosinase in order to achieve the purpose of inhibiting melanin formation

50 It is thought that this increase in nitrosative stress is involved in neurodegeneration seen in epilepsy

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