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In Handbook of Uncertainty Quantification (eds Ghanem, R., Higdon, D

It features hydrolyzed collagen, L-lysine, and vitamin C as shown in the ingredients section

Patterson AD, Carlson BA, Li F, Bonzo JA, Yoo MH, Krausz KW, et al

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Patients have been treated for a decade or more on the basis of a mistaken diagnosis of dermatological disease when pruritus was not accompanied by jaundice