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High doses of IGF-1 administration typically results in hypoglycaemia despite the potent suppression of circulating insulin concentrations it triggers [134, 135, 158]

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is supported by the NUHS Internal Grant Funding under NUS Start-up grant NUHSRO/2022/047/Startup/11, an MOE Tier 2 grant T2EP30124-0014, and a Vidi grant from the Netherlands Organization for Scientific Research (NWO