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Around 1 - 20 % of drug from the dose becomes available to the body by a transdermal route

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table 8.8 to 8.12 show various changes observed at stress condition A-Thermal stress Table no 22: Thermal stability study at 50?C Table no 23: Thermal stability study at 70?C Table no 24: Thermal stability study at 90?C B photostability study Table no 25: Photostability stability study Table no 26: Photostability stability study Table no 27: Photostability stability study (III.2.H) MUCOADHESIVE TESTING This result of Mucoadhesive testing conclude that formulation is having appropriate mucoadhesive character so that it can show bio adhesion with sublingual mucosa -0.50 value shows good mucoadhesive character due to presence of chitosan matrix in the solution

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