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Funding The present study was supported by grants from the National Institute of Health (NIH): DA044872

Acute liver failure from paracetamol toxicity has a high mortality rate of 30% if there is no liver transplantation available[89,90]

Quantitative real-time PCR (qRT-PCR) was performed using the BeyoFast SYBR Green One-Step qRT-PCR Kit (Beyotime, China) on an MX3000P Real-time PCR system (Stratagene, Germany)

Aging 32 , 12621272 (2011)

Its relevance to neuropathy is most direct in the metabolic neuropathies, particularly diabetic peripheral neuropathy, where impaired glucose metabolism, insulin resistance, and mitochondrial dysfunction all contribute to nerve damage