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Glutamine promotes the generation of B10(+) cells via the mTOR/GSK3 pathway

10.3389/fcvm.2022.1057985 180 XiaoJ.LiN.XiaoS.WuY.LiuH

(PubMed) Taylor AJ, Sullenberger LE, Lee HJ, Lee JK, Grace KA

Therefore, a strategy that concurrently modulates metabolic pathways and disrupts intercellular communication represents a potential synthetic lethal approach, providing a novel direction for the systematic targeting of tumors and the improvement of therapeutic efficacy [372]

Oridinon (Ori), a natural terpenoid derived from the plant Isodon rubescens (Hemsl.), can increase cardiac Gln levels and inhibit the decline of ATP/ADP ratio, protecting cardiomyocytes and reducing infarct size in a rat model of myocardial injury