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Using them twice daily when your skin only needs them once, or applying a high-concentration serum when a moderate one would suffice, can overwhelm your skin's ability to maintain its moisture barrier

Proc Natl Acad Sci U S A 112:1185211857

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Standard IV dosing for wellness applications ranges from 600 to 1,800 mg per session depending on the indication

One example is KSM-66 ashwagandha, a well-known extract that has been evaluated in multiple clinical trials, including randomized, double-blind, placebo-controlled studies