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CpG sites with FDR less than 0.05 in the linear regression models were determined as differentially methylated positions, and CpG sites with FDR less than 0.05 in the DiffVar tests were determined as variably methylated positions

[69] Though n-acetylcysteine has been used in patients of polycystic ovarian syndrome and resulting hyperandrogenism in several clinical trials, a recent meta-analysis of eight clinical trials has shown that acne and hirsutism do not improve significantly when compared with placebo

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In another study with 118 CRC patient cases, HO-1 expression was significantly elevated in CRC tumor tissues when compared to paired normal non-tumoral and polyps samples