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Consequently, compared with nontargeted formulations (550 mg/kg), TPP-functionalized nanoparticles achieve therapeutic efficacy at substantially lower doses (25 mg/kg for CUR), thereby minimizing systemic exposure while preserving mitochondrial bioenergetics, the membrane potential, and dynamics [16]

doi: 10.1053/j.gastro.2013.02.006

Human gastroenteropancreatic expression of melatonin and its receptors MT1 and MT2

However, many commensal microbes within our body can act in beneficial or harmful ways depending on their environment (health, stress level, and access to different nutrients)

Doctors also prescribe folic acid supplements, blood transfusions, and antibiotics for these patients