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[11] By ramping up the dosage slowly, patients can often avoid side effects like headache or nausea while still obtaining the energizing or cognitive benefits of NAD+

Elevations in blood pressure (180 mmHg systolic or 110 mmHg diastolic) were observed in approximately 18% of healthy subjects (not exposed to cyanide) receiving hydroxocobalamin 5 g and 28% of subjects receiving 10 g

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