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In the same study, a plasma clearance of 7.2 mL/min was determined, resulting in a median biological half-life of 9.4 h (Degen et al

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Saikali, Z., and Singh, G., Doxycycline and other tetracyclines in the treatment of bone metastasis, Anticancer

Due to its excellent biocompatibility, biodegradability, and drug-loading capacity, ALG nanoparticles (NPs) are readily degraded in biological systems, thereby reducing the risk of long-term accumulation (198)