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Accordingly, we hypothesized that inhibition of RNR function may suppress ferroptosis by reducing the draw on the existing GSH pool, which can then be re-routed to suppress ferroptosis

Ojanotko, A., Nienstedt, W

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In a first study [128], nine patients (eight males and one female) receiving choline esterase inhibitors were treated with ALA (600 mg/day) for about 1 year