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Pharmacokinetics: Mild symptoms : Patients exhibiting two or more mild symptoms of organophosphate poisoning (Table 1) : Administer one DuoDote injection intramuscularly into the lateral thigh muscle or buttocks (holding the injector for 10 seconds after it fires)

10.1158/0008-5472.CAN-20-1641 36 ForcinaG

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244, 245, 246, 247 This raises the intriguing possibility that pharmacological inhibitors of DNA methyltransferases and histone deacetylases, some of which are currently approved by international regulatory agencies for use in cancer patients, may limit CDDP resistance at least in part by modulating the abundance of specific microRNAs

R., & Morris, P