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Dapagliflozin inhibits the ubiquitylation-degradation of SLC7A11 (287) and mitigates renal tubular ferroptosis in DKD

Studies in fast-aging XpdTTD/TTD mouse models reveal comprehensive rejuvenation effects following FOXO4-DRI administration

The change in each parameter was observed and compared

Eur J Biochem 209(1):437444 Saleh RNM, West AL, Ostermann AI, Schebb NH, Calder PC, Minihane AM (2021) APOE genotype modifies the plasma oxylipin response to omega-3 polyunsaturated fatty acid supplementation in healthy individuals