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A feedback stimulation of collagen repair has also been proposed for this peptide, but the main benefit to photoaged skin is believed to be the enhanced delivery of copper.

Szulc A, Konarzewska B, Galinska-Skok B, Lazarczyk J, Waszkiewicz N, Tarasow E, et al

Arginine on the surface of the heavy ferritin chain FTH1 binds to a C-terminal domain of NCOA4 when iron levels are low, thereby promoting the transfer of autophagosomes to lysosomes (Mancias et al., 2015