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For example, activation of the IRE1-XBP1 pathway produces XBP1s, which participates in the adaptive regulation of ERS and indirectly influences necroptosis by regulating the expression of certain anti-apoptotic proteins (Wang S

4 The therapeutic targets and drugs of PCOS Given the multifactorial pathogenesis of PCOS, therapeutic strategies rarely involve a single intervention

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Consequently, it is imperative to explore the enzyme that mediates its endogenous generation, namely, lactyl-CoA synthase