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RIPK1 and death receptor signaling drive biliary damage and early liver tumorigenesis in mice with chronic hepatobiliary injury

On the mechanism of growth hormone-induced stimulation of renal acidification in humans: effect of dietary NaCl

doi: 10.1038/ki.1991.277

A synthetic peptide appears to directly disrupt the destructive inflammation that occurs in nephritis, enabling the kidneys to better recover and maintain their important functions, investigators report

Reportedly, the blood concentration of pirfenidone 5-carboxy-pirfenidone metabolite excreted through the kidneys significantly increases in patients with severe renal impairment (area under the curve of mild, moderate, and severe renal impairment was 49.3, 100, and 168 mghr/L, respectively