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Accumulating evidence links such mitochondrial remodeling in females to oxidative stress and altered neuronal excitability as mechanisms through which diverse early-life stressors become biologically embedded, leading to sustained changes in cellular energetics and circuit function [68, 69, 70]

Comparison of in vivo immunomodulatory effects of intravenous and intraperitoneal administration of adipose-tissue mesenchymal stem cells in experimental autoimmune encephalomyelitis (EAE)

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After oral administration, the majority of curcumin is excreted as metabolites, with only a small fraction entering the bloodstream, at concentrations well below those required to inhibit most of its anti-inflammatory targets