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IL-15) and fibroblast behavior between species

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Among the candidate senotherapeutic agents, Metformin is the most extensively tested in clinical trials for a variety of age-related pathologies

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Subsequent to the treatment, the media was substituted with MTT solution (2 mg/mL in PBS), diluted with fresh medium at a 3:1 ratio, yielding a final volume of 200 L per well

In this study, we employed targeted metabolomic profiling in two distinct murine models of lung inflammation: one induced by LPS, a bacterial endotoxin that simulates infectious pneumonia, and the other induced by papain, a cysteine protease that models allergic and non-infectious airway injury ( in vivo and in vitro