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Causes and consequences of oxidative stress in spermatozoa

All authors participated in the preparation of the manuscript and approved the final manuscript

However, they do not yet provide robust longterm comparative outcome data (toxicity, quality of life [QoL], tumor control) sufficient to demonstrate a widened therapeutic window in this indication

received funding from DFG under Germanys Excellence Strategy EXC-2049 390688087, Collaborative Research Center ReTune TRR 295-424778381, Clinical Research Group KFO 5023 BeCAUSE-Y, project 2 EN343/16-1

Despite plentiful evidence showing improvement in acne, several studies have failed to show a significant reduction in sebum output after PDT with ALA.[67,68] However, one supportive study found that lower sebum excretion persisted even 20 weeks after multiple PDT sessions, but not after a single PDT session