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Water retention is possible but less common with Sermorelin than with direct HGH

Contrarily, the erectile dysfunction may be due to altered autocrine/paracrine actions of GH, as erection requires relaxation of penile smooth muscle and modulation of blood flow

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However, mAb treatment tended to oppose age-related changes in 30 of these metabolites (22 marginally significant after FDR correction), including a reduction in the age-related rise of many glycerophospholipids, and a distinct clustering of metabolites from heart tissue in Old Con versus Old mAb-treated animals by PCA (Supplementary Fig