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Science 370 , 856860 (2020)

(2019) systematically identified GABA-producing bacteria in the human gut, reporting that multiple Bacteroides species produce substantial amounts of GABA

median age 46 years)

doi: 10.1016/j.addr.2013.08.008 153 El OuaamariYVan den BosJWillekensBCoolsNWensI

9,394,338 Applications Treatment for Alzheimers and other neurodegenerative diseases Key Benefits & Differentiators Increased stability: Resistance to -glutamyl transpeptidase (-GT) breakdown leads to extended antioxidant activity Replicates endogenous GSH activity: Crosses the blood-brain barrier and mimics key glutathione (GSH) functions Technology Overview Oxidative stress and plaque formation from glycation are key features of numerous neurodegenerative diseases, including Alzheimers disease