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2.5 Potential biomarkers of ferroptosis Translating ferroptosis from a mechanistic concept into a clinical tool for IPF will require reliable, minimally invasive biomarkers that reflect iron overload, lipid peroxidation, and antioxidant failure in the lung

Crucially, this predictive value was only evident in the BEV treatment group and disappeared in the cytotoxic drug-only treatment group, suggesting MMP-2 is a predictive biomarker specific to BEV efficacy (64)

Research protocols with documented outcomes consistently use 46 hoursdeviations reduce consistency and magnitude of metabolic improvements