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Another major piece of the chronic illness puzzle is the NO/ONOO- (Nitric Oxide/Peroxynitrite) cycle, a mechanism heavily researched in the context of ME/CFS and post-viral fatigue

Clinical questionnaires commonly used in practice, like the DN4 (Douleur Neuropathique 4), LANSS (Leeds Assessment of Neuropathic Symptoms and Signs), and NTSS-6 (Neuropathy Total Symptom Score-6), among others, exhibit restricted diagnostic precision, demand substantial time for completion, and produce varying prevalence estimates for PN due to inconsistencies in agreement on sensitivity and specificity [34]

It also has powerful anti-inflammatory effects without suppressing your immune system like traditional anti-inflammatory medications can

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Both forms are found in research contexts