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For instance, the release of Smac/Diablo into the cytosol ensures the efficiency of caspase 3 in proteolyzing target proteins through inhibition of inhibitor of apoptosis proteins (IAPs)

Esquirol Y, Bongard V, Mabile L, Jonnier B, Soulat JM, Perret B (2009) Shift work and metabolic syndrome: respective impacts of job strain, physical activity, and dietary rhythms

The symptoms of CIPN are primarily felt in the hands and feet with some combination of numbness, tingling, shooting or stabbing pain, burning pain, cramping, and hypersensitivity to cold temperatures (e.g., cold weather, touching something cold) (Staff et al., 2017

If it doesnt, your doctor may prescribe medications for both conditions

S.MavaddatH.PeyrovinasabA.Ghasemi ZargarS.Sirous KabiriS.et al (2024)