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In the phase II trials, a reduction in the tumor size was seen in the patients with platinum resistant ovarian cancer and lung cancer (Pham et al., 2015)

doi: 10.3390/medicina57040347 4 SunKYFanYWangYXZhongYJWangGF

The dark side of curcumin

Radicicol and geldanamycin, both Hsp90 inhibitors, enhance azole efficacy by disrupting membrane integrity and capsule formation, impairing Hsp90 mitochondrial localization, and increasing reactive oxygen species in fungal pathogens (Cordeiro et al., 2016