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Progressive supranuclear palsy (PSP)

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Obstetricians have prescribed it for morning sickness since the 1940s, and the American College of Obstetricians and Gynecologists still recommends it as a first-line treatment for pregnancy-related nausea

To perform virtual screening using pharmacophore model ensembles coupled with YN2, 5 parameters were required: the number of stable and unstable conformations, the minimum ensemble phase score value among known active molecules (, the maximum ensemble phase score value among known active molecules , and the YN2 threshold