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Alterations in NO-mediated endothelium-dependent vasodilation results in widespread vasoconstriction and coagulation abnormalities and is considered to be an early step in the development of atherosclerosis

Some researchers have studied vitamin B12 to find out if it can increase energy and endurance during exercise, but the results are inconclusive

doi: 10.1016/j.jad.2014.01.020 244 MolendijkMMoleroPSnchez-PedreoFOvan der DoesWMartnez-GonzlezMA