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10.1038/s41593-019-0479-z Nat

repeated high dosing may lower copper levels, so monitoring is key

13.3 [11.1-16.4] mol/L

In contrast, Glu induces oxidative stress and apoptosis in ECs [58]

Another study has reported that metformin seemingly increases the production of 3-hydroxy fatty acids (3-HFAs) either by beta-oxidation or via gut microbiota