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Across those trials, AOD-9604 demonstrated a strong safety profile adverse events were comparable to placebo, no genotoxicity was found, and it showed no negative effect on glucose or insulin sensitivity

We discovered that Diphenyleneiodonium chloride (DPI), an inhibitor of flavoprotein enzymes and mitochondrial complex I, synergizes with mitoquinone mesylate (MitoQ), a mitochondria-targeted antioxidant in 2D and 3D in vitro models of NB

Intracellular lipid droplets were stained with Oil Red O and visualized under a light microscope (Olympus, Tokyo, Japan)

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