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Report of the Joint FAO/WHO Expert Committee on Food Additives, 24 June-2 July 1970 Rome, Food and Agriculture Organization, pp 86-8

2005;5, article 32 doi: 10.1186/1471-2261-5-32

The following linear gradient at 400 L/min flow rate with a column temperature at 55 C was used: 02 min: 60%B, 22.3 min: 75% B, 2.310 min: 90%B, 1017 min: 100%B, 1720 min: 40%B

Symptoms of Acanthosis Nigricans Common symptoms include: Dark brown or black patches Thickened skin texture Velvety appearance Skin tags in affected areas Mild itching or odor in some cases These symptoms are usually visible around the neck and underarms , which can affect a persons confidence

Inclusion and ethics statement All co-authors on this study have met the criteria for authorship outlined by Nature Portfolio journals, and the roles and responsibilities of each author were agreed among researchers