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[6] [7] [10] GPx1 typically uses glutathione (GSH) as the reductant, but when glutathione synthetase (GSS) is, as in brain mitochondria, -glutamylcysteine can serve as the reductant instead

Reduced shedding often precedes visible thickening

[PMC free article: PMC4110209] [PubMed: 25067957] 229

As a naturally occurring neuropeptide with a research history spanning several decades, it offers a distinct profile compared to conventional sleep medications one focused on supporting the bodys own sleep architecture rather than chemically inducing sedation