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These parameters indicate the maintenance of a more reducing redox environment in Plainsman which may contribute to its better drought tolerance due to the efficient removal of the excess of ROS (Considine and Foyer 2014a)

The activation of AMPK broadly suppresses proinflammatory signaling pathways, including the JAK-STAT, NF-B, C/EBP, CHOP, and HIF-1 pathways, which in turn inhibits the expansion and immunosuppressive function of myeloid-derived suppressor cells (MDSCs) 42

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