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No human clinical trials have been published

And its one where the chemistry gives a clearer answer than most compounds in this space

Strongest human evidence The METAOD006 (OPTIONS) Phase 2b trial randomized 502 adults with obesity (BMI 30-45 kg/m^2) to oral AOD-9604 (0.25, 0.5, or 1 mg/day) or placebo for 24 weeks alongside a supervised diet and exercise program

Some people may also suffer from pernicious anemia, which inhibits the body from being able to absorb enough vitamin B12, causing a deficiency

In metabolic research models, high-fat diets typically lead to hypertrophy (enlargement) of WAT cells and a slowdown in their metabolic rate